Press Release

INDIANAPOLIS and THOUSAND OAKS, FIFA 2026开球时间 Calif., Sept. 17, 2020 /PRNewswire/– Eli 2026世界杯直播赛程 Lilly and Company (NYSE:LLY) and Amgen (NASDAQ:AMGN) today announced a global antibody 世界杯直播频道 manufacturing collaboration to 世界杯比赛时间 FIFA 2026开球时间 significantly increase the supply capacity available for Lilly's potential 2026世界杯直播赛程 COVID-19 therapies. Lilly is currently studying 2026世界杯直播赛程 several potential neutralizing antibodies for the prevention and/or treatment of 世界杯比赛时间 世界杯比赛时间 COVID-19 as either monotherapy or in FIFA 2026开球时间 combination. Through this collaboration, the two companies will have the ability to quickly scale up production and serve many 世界杯比赛时间 more patients around the world should 世界杯直播频道 one FIFA 2026开球时间 世界杯比赛时间 or more of Lilly's antibody therapies prove successful in clinical testing and receive regulatory approval.

"Based on our initial clinical studies, we believe FIFA 2026开球时间 that virus neutralizing antibodies, including LY-CoV-555, could play an important role in the fight against COVID-19," said Daniel Skovronsky, M.D., Ph.D., Lilly's 世界杯直播频道 世界杯比赛时间 2026世界杯直播赛程 世界杯直播频道 chief scientific officer and president of Lilly Research Laboratories. "Increasing the manufacturing capacity for our neutralizing antibodies through this collaboration with Amgen is a crucial next step, and 世界杯直播频道 together we hope to be able to 世界杯比赛时间 produce many millions 世界杯比赛时间 of doses even next year."

"We are impressed with Lilly's data, in particular the reduction in hospitalizations, and are enthusiastic about the potential for these neutralizing antibodies as a therapeutic for COVID-19," said David M. 世界杯比赛时间 世界杯比赛时间 FIFA 2026开球时间 世界杯比赛时间 世界杯直播频道 Reese, M.D., executive vice president of research and development at Amgen. Esteban Santos, executive vice president of Operations at Amgen, 世界杯比赛时间 added "we are proud FIFA 2026开球时间 to partner with Lilly and FIFA 2026开球时间 leverage our deep 世界杯直播频道 FIFA 2026开球时间 世界杯比赛时间 technical expertise in 世界杯直播频道 antibody development and, in particular, our strong capabilities in the scale up and manufacturing of complex biologics. This is yet another example of FIFA 2026开球时间 the ways our industry is closely 世界杯直播频道 FIFA 2026开球时间 世界杯比赛时间 collaborating to combat this devastating disease FIFA 2026开球时间 and help patients around the world access new therapies."

About 世界杯比赛时间 Amgen

Amgen is committed to unlocking the potential of biology for patients suffering from serious 世界杯直播频道 illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins 世界杯直播频道 世界杯直播频道 by 世界杯比赛时间 using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology.

Amgen focuses on areas of high 世界杯比赛时间 unmet medical need and leverages its expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has 世界杯直播频道 世界杯直播频道 grown to be one 世界杯比赛时间 of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. 世界杯比赛时间 2026世界杯直播赛程

For more information, visit www.amgen.com and follow FIFA 2026开球时间 us on www.twitter.com/amgen.

About Eli Lilly and Company

Lilly is a global health care leader that 世界杯比赛时间 unites caring with 世界杯比赛时间 discovery to create medicines that make life better for people around the world. FIFA 2026开球时间 We were founded 世界杯直播频道 more than a century ago 2026世界杯直播赛程 by a man committed to creating 世界杯直播频道 世界杯直播频道 FIFA 2026开球时间 FIFA 2026开球时间 世界杯比赛时间 high-quality medicines that meet real needs, and today we remain true to 世界杯直播频道 that mission in all our 世界杯直播频道 work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those 2026世界杯直播赛程 who need 世界杯直播频道 FIFA 2026开球时间 2026世界杯直播赛程 FIFA 2026开球时间 世界杯比赛时间 them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at http://www.lilly.com.and FIFA 2026开球时间 http://www.lilly.com/news. 世界杯比赛时间 C-LLY 2026世界杯直播赛程 世界杯比赛时间 FIFA 2026开球时间 FIFA 2026开球时间 世界杯比赛时间

Amgen Forward Looking Statements

This news release contains forward-looking FIFA 2026开球时间 statements that are based on the current expectations and beliefs of Amgen. All statements, other than statements of historical fact, are statements that could be deemed 世界杯比赛时间 世界杯直播频道 forward-looking statements, including FIFA 2026开球时间 any statements on the 世界杯直播频道 outcome, benefits and synergies of collaborations, or potential collaborations, 世界杯比赛时间 with any other FIFA 2026开球时间 company, including BeiGene, Ltd. or any collaboration 世界杯比赛时间 2026世界杯直播赛程 FIFA 2026开球时间 世界杯比赛时间 or potential collaboration in pursuit of therapeutic antibodies against COVID-19 (including statements 世界杯直播频道 regarding such collaboration's, FIFA 2026开球时间 or our own, ability to discover and 世界杯比赛时间 develop fully-human neutralizing FIFA 2026开球时间 antibodies targeting SARS-CoV-2 or antibodies against targets other than the SARS-CoV-2 receptor binding domain, and/or to produce any such antibodies to potentially prevent or treat COVID-19), or the Otezla® (apremilast) 世界杯比赛时间 世界杯比赛时间 FIFA 2026开球时间 acquisition (including anticipated Otezla sales growth and the timing of non-GAAP EPS accretion), as well as estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, 世界杯直播频道 FIFA 2026开球时间 世界杯比赛时间 FIFA 2026开球时间 expected FIFA 2026开球时间 legal, arbitration, political, regulatory or clinical results or practices, customer and prescriber patterns or practices, reimbursement 世界杯直播频道 activities 世界杯比赛时间 and outcomes, effects of pandemics or other widespread health problems such as the ongoing COVID-19 pandemic on our business, outcomes, progress, or effects relating to studies of Otezla as a potential treatment for COVID-19, 世界杯直播频道 and 世界杯直播频道 世界杯比赛时间 other FIFA 2026开球时间 such estimates and results. Forward-looking 世界杯直播频道 世界杯直播频道 statements involve significant risks and uncertainties, including those discussed below 世界杯直播频道 and FIFA 2026开球时间 more fully described FIFA 2026开球时间 in the Securities and Exchange Commission reports filed by Amgen, including our most recent 世界杯直播频道 世界杯直播频道 FIFA 2026开球时间 annual report on FIFA 2026开球时间 Form 10-K and any subsequent periodic reports on Form FIFA 2026开球时间 10-Q and current reports on Form 8-K. Unless otherwise noted, Amgen is providing FIFA 2026开球时间 this information as of the date 世界杯直播频道 of FIFA 2026开球时间 this news release 世界杯直播频道 世界杯直播频道 and does not undertake any obligation to update any forward-looking statements contained in this document as a result of new information, future events or otherwise.

No forward-looking statement can be guaranteed and actual results may differ materially from those we project. Our results may be 世界杯比赛时间 affected by our ability to successfully market both new and existing products 世界杯直播频道 世界杯直播频道 世界杯直播频道 2026世界杯直播赛程 FIFA 2026开球时间 世界杯直播频道 domestically and internationally, clinical and regulatory developments involving current and future products, sales growth of recently launched products, competition from other products including biosimilars, FIFA 2026开球时间 FIFA 2026开球时间 difficulties or delays in manufacturing our products and global economic conditions. In addition, sales of FIFA 2026开球时间 our products are affected by pricing pressure, political and public scrutiny and reimbursement policies 2026世界杯直播赛程 世界杯直播频道 2026世界杯直播赛程 FIFA 2026开球时间 世界杯直播频道 imposed by third-party 世界杯直播频道 payers, including governments, private insurance 2026世界杯直播赛程 plans and managed care providers and may be affected by regulatory, clinical and 世界杯直播频道 guideline FIFA 2026开球时间 developments and domestic and international FIFA 2026开球时间 2026世界杯直播赛程 FIFA 2026开球时间 trends toward managed care and healthcare cost containment. 世界杯比赛时间 Furthermore, our research, testing, pricing, marketing and other operations are subject to extensive regulation by domestic and foreign government 世界杯比赛时间 世界杯直播频道 世界杯比赛时间 世界杯直播频道 regulatory authorities. We or others could identify safety, side effects or manufacturing problems with our products, including our devices, after they are on the market. Our business may be impacted by 2026世界杯直播赛程 government investigations, 世界杯比赛时间 litigation and product liability claims. In addition, our business may be impacted by the adoption of new tax 世界杯比赛时间 legislation 2026世界杯直播赛程 or exposure to additional tax liabilities. If we fail FIFA 2026开球时间 世界杯直播频道 世界杯直播频道 to meet the compliance obligations in the corporate integrity agreement between us and the U.S. government, we could become subject to significant sanctions. Further, while we routinely obtain patents for 世界杯直播频道 2026世界杯直播赛程 世界杯直播频道 our products and technology, the protection offered by our patents FIFA 2026开球时间 and patent applications may FIFA 2026开球时间 be 世界杯比赛时间 challenged, invalidated or circumvented by our competitors, or 世界杯比赛时间 we may fail to prevail in present and future 世界杯直播频道 世界杯直播频道 FIFA 2026开球时间 intellectual property litigation. We perform a substantial amount of our commercial manufacturing activities at a few key facilities, including in Puerto Rico, and also depend on third parties for a portion 世界杯比赛时间 2026世界杯直播赛程 of our manufacturing 世界杯直播频道 activities, and limits on supply may constrain FIFA 2026开球时间 sales of certain of our 世界杯直播频道 current products and product candidate development. An outbreak 世界杯直播频道 of disease or similar public health threat, such 2026世界杯直播赛程 as 世界杯比赛时间 COVID-19, and the public and governmental effort to mitigate against the spread of such disease, could have a significant adverse effect 世界杯直播频道 on the 2026世界杯直播赛程 supply of materials for our 世界杯比赛时间 manufacturing activities, the distribution of our products, the commercialization of our product candidates, and our clinical trial operations, and any such events may have a material adverse effect on our product development, product 世界杯比赛时间 FIFA 2026开球时间 sales, business and results of operations. We rely on collaborations with third parties for the development of some of our product candidates and for the commercialization and sales of 世界杯比赛时间 some of our commercial FIFA 2026开球时间 世界杯比赛时间 FIFA 2026开球时间 2026世界杯直播赛程 products. In addition, we compete with other companies with respect to many of our marketed products as 世界杯比赛时间 well as for the discovery and development of new products. Discovery or identification of new product 世界杯比赛时间 世界杯直播频道 世界杯直播频道 candidates or 世界杯比赛时间 development of new indications for existing products cannot be guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that 世界杯直播频道 any particular product 世界杯比赛时间 candidate or development of a new indication for an existing product will be successful and become a commercial product. Further, some raw materials, medical devices and component parts for our products FIFA 2026开球时间 世界杯比赛时间 2026世界杯直播赛程 FIFA 2026开球时间 世界杯比赛时间 are supplied by sole third-party suppliers. Certain of our distributors, customers and payers have substantial purchasing leverage in their dealings with us. The discovery of significant 世界杯比赛时间 problems with a 世界杯比赛时间 2026世界杯直播赛程 product similar to one of our products that implicate an 2026世界杯直播赛程 entire class of products could have a material adverse effect on sales of the affected products and on our business and results of operations. Our FIFA 2026开球时间 2026世界杯直播赛程 efforts to collaborate with or acquire other 世界杯比赛时间 companies, products or 世界杯直播频道 technology, and to integrate the 世界杯直播频道 operations of companies or to support the products or technology we have acquired, may not be successful. 世界杯比赛时间 世界杯比赛时间 A FIFA 2026开球时间 breakdown, cyberattack or information security breach could compromise the confidentiality, integrity and availability of our systems and 世界杯直播频道 our data. Our stock price is volatile and may be affected by a 2026世界杯直播赛程 FIFA 2026开球时间 number of events. Our business performance could 世界杯比赛时间 affect or FIFA 2026开球时间 limit the ability of our Board of Directors to declare a dividend or our ability to pay a dividend or repurchase our 2026世界杯直播赛程 common stock. We may not be 世界杯直播频道 FIFA 2026开球时间 世界杯直播频道 2026世界杯直播赛程 FIFA 2026开球时间 able to access the capital and credit markets on terms that are favorable to us, or at all.

Lilly Forward Looking Statements

This press release contains forward-looking statements about the FIFA 2026开球时间 supply and use of Lilly antibodies to treat or prevent COVID-19 2026世界杯直播赛程 世界杯直播频道 and reflects Lilly's current beliefs. However, as with any such undertaking, there 世界杯比赛时间 世界杯比赛时间 世界杯直播频道 FIFA 2026开球时间 are substantial risks and 世界杯比赛时间 uncertainties in the process of drug development and commercialization. Among other 世界杯直播频道 things, there can be no guarantee that Lilly antibodies will prove to be safe FIFA 2026开球时间 and effective to 2026世界杯直播赛程 世界杯直播频道 世界杯比赛时间 treat or prevent COVID-19, that any Lilly antibody will receive regulatory approval, or that we can 世界杯比赛时间 provide an adequate supply of Lilly antibodies. For a further discussion of these and other risks and uncertainties FIFA 2026开球时间 FIFA 2026开球时间 2026世界杯直播赛程 that could cause actual results 世界杯直播频道 to differ from Lilly's expectations, please see Lilly's most recent Forms 10-K and 10-Q filed with the U.S. Securities and Exchange Commission. Lilly undertakes no duty to 2026世界杯直播赛程 update forward-looking statements.