Goal Is to Bring Amgen’s 世界杯直播频道 Vectibix® (Panitumumab) to Chinese Patients
THOUSAND OAKS, Calif., and Zhejiang, China (May 9, 2013) – Amgen (NASDAQ:AMGN) and Zhejiang Beta Pharma Co., Ltd. (Zhejiang Beta Pharma) today announced that the companies have signed an agreement to form
世界杯比赛时间 观看比赛直播 世界杯直播频道 a joint venture to commercialize Amgen’s Vectibix® (panitumumab) in the Chinese market. Together, Amgen and Zhejiang Beta Pharma aim to quickly and efficiently deliver Vectibix to patients in China.
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The joint venture will 观看比赛直播 benefit from Zhejiang Beta Pharma’s FIFA 2026开球时间 观看比赛直播 strong expertise in the development and commercialization of molecularly targeted therapies as 2026世界杯直播赛程 世界杯比赛时间 well as Zhejiang Beta Pharma’s industry-leading oncology
世界杯比赛时间 FIFA 2026开球时间 观看比赛直播 sales network in China. Zhejiang Beta Pharma’s China capabilities are complementary 观看比赛直播 to Amgen’s global expertise in the development 观看比赛直播 and manufacturing of human therapeutics. 2026世界杯直播赛程
“This joint venture brings us one step closer to providing Chinese patients with Amgen’s medicines and supports our 世界杯比赛时间 strategy FIFA 2026开球时间 of expanding in key, fast-growing markets,” said Anthony C. 观看比赛直播 Hooper, executive
世界杯直播频道 观看比赛直播 世界杯直播频道 FIFA 2026开球时间 世界杯直播频道 FIFA 2026开球时间 世界杯直播频道 世界杯比赛时间 vice president 观看比赛直播 at Amgen. “We are pleased to have the opportunity to join forces with Zhejiang Beta Pharma, a leader in developing 世界杯直播频道 and commercializing innovative medicines that shares our goal of making
世界杯直播频道 世界杯比赛时间 a new 世界杯直播频道 treatment option available to colorectal cancer patients in China.”
“Amgen is a pioneer and 世界杯比赛时间 a global leader in the 世界杯直播频道 biotech industry. Our partnership with Amgen will be of long-term strategic 世界杯直播频道 significance not only for Zhejiang Province, but also for the whole medical community
世界杯比赛时间 FIFA 2026开球时间 世界杯比赛时间 观看比赛直播 世界杯直播频道 in China,” said Lieming Ding, chairman of Zhejiang Beta Pharma. “We share Amgen’s passion for developing molecularly targeted therapies for unmet 世界杯比赛时间 medical needs, and are confident that FIFA 2026开球时间 together we can
FIFA 2026开球时间 世界杯比赛时间 世界杯直播频道 FIFA 2026开球时间 世界杯比赛时间 help many Chinese FIFA 2026开球时间 patients who suffer from colorectal cancer.”
“This is an 世界杯直播频道 FIFA 2026开球时间 important step forward in Amgen’s commitment to the China market,” said James Li, vice president and general manager, Amgen 2026世界杯直播赛程 Greater China. “We are excited about the formation of our partnership
2026世界杯直播赛程 2026世界杯直播赛程 世界杯比赛时间 with Zhejiang Beta Pharma and look forward to bringing Vectibix to Chinese patients within the coming years. Amgen’s 30-year track record of developing innovative medicines means we are well-positioned
2026世界杯直播赛程 世界杯直播频道 世界杯比赛时间 观看比赛直播 FIFA 2026开球时间 世界杯比赛时间 to support the development of China’s biotech sector. We see this 世界杯直播频道 as 世界杯比赛时间 a clear step that enables 观看比赛直播 Amgen to help China achieve its 2026世界杯直播赛程 goals for the biotech industry.”
“This is certainly a 2026世界杯直播赛程 groundbreaking event for the biotech industry in China,” said Yinxiang Wang, CEO of Zhejiang Beta Pharma. “We are pleased to be joining 世界杯直播频道 forces with Amgen in the war FIFA 2026开球时间 世界杯比赛时间 against cancer.”
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According to the agreement, FIFA 2026开球时间 the new joint venture will be named Amgen-Beta Pharmaceuticals Co., Ltd. (贝达安进制药有限公司). Zhejiang Beta Pharma will own 51 percent and Amgen will own the remaining 49 percent interest
世界杯比赛时间 世界杯比赛时间 2026世界杯直播赛程 in the joint venture. The creation of the 世界杯比赛时间 joint venture is FIFA 2026开球时间 subject to the satisfaction of certain closing conditions, including the approval of relevant government authorities in China.
About Amgen
Amgen discovers, develops, manufactures and delivers innovative human therapeutics. A biotechnology pioneer since 1980, FIFA 2026开球时间 Amgen was one of the first companies to realize the
FIFA 2026开球时间 世界杯直播频道 观看比赛直播 世界杯直播频道 世界杯直播频道 观看比赛直播 FIFA 2026开球时间 new science’s promise 世界杯直播频道 by bringing safe, FIFA 2026开球时间 2026世界杯直播赛程 世界杯比赛时间 effective medicines from lab to manufacturing plant to 世界杯比赛时间 patient. Amgen therapeutics have changed the practice of medicine, helping people around the world in the
观看比赛直播 观看比赛直播 世界杯比赛时间 fight 世界杯直播频道 against serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives. For more information,
FIFA 2026开球时间 visit http://wwwext.amgen.com and follow us on www.twitter.com/amgen.
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About 2026世界杯直播赛程 Zhejiang Beta Pharma Co., Ltd.
Zhejiang 世界杯直播频道 Beta Pharma is a leading 2026世界杯直播赛程 innovative pharmaceutical company 世界杯比赛时间 in China with fully integrated capabilities that include R&D, GMP manufacture,
世界杯直播频道 2026世界杯直播赛程 世界杯直播频道 FIFA 2026开球时间 sales and marketing. We were founded in 2003 and are headquartered in Hang-Zhou with R&D operations in Beijing. Over the FIFA 2026开球时间 last 10 years, we have been dedicated to the development 世界杯比赛时间 of novel 世界杯直播频道 therapeutics
世界杯直播频道 观看比赛直播 世界杯比赛时间 and launched Icotinib in 2011 for the treatment of NSCLC patients in China. Going forward, we will FIFA 2026开球时间 continue to focus on pharmaceutical innovation so that we can benefit many more patients. For more information,
2026世界杯直播赛程 世界杯比赛时间 世界杯比赛时间 观看比赛直播 visit www.betapharma.com.cn.
About Vectibix
Vectibix is a prescription medicine 观看比赛直播 used for the treatment of metastatic colorectal cancer (mCRC). It is grouped within a class of medications called biologics, which
世界杯比赛时间 世界杯直播频道 世界杯比赛时间 FIFA 2026开球时间 are therapies derived from human cells. Vectibix is approved in more than 40 countries.
Vectibix is the first 世界杯比赛时间 fully human anti-epidermal growth factor receptor (EGFR) antibody approved by the U.S. Food and Drug Administration (FDA) for the treatment of FIFA 2026开球时间 metastatic colorectal 观看比赛直播 cancer (mCRC). Vectibix
2026世界杯直播赛程 世界杯直播频道 世界杯直播频道 世界杯直播频道 FIFA 2026开球时间 世界杯直播频道 was approved in the U.S. in September FIFA 2026开球时间 2006 as a single agent for the treatment of metastatic FIFA 2026开球时间 colorectal carcinoma with disease progression on or following fluoropyrimidine, oxaliplatin and irinotecan
FIFA 2026开球时间 FIFA 2026开球时间 chemotherapy regimens. Approval is based 2026世界杯直播赛程 on progression-free survival; no data demonstrate an improvement in disease-related symptoms 观看比赛直播 or increased survival with Vectibix.
Retrospective subset analyses of metastatic colorectal cancer trials have not shown a treatment benefit for Vectibix in patients whose FIFA 2026开球时间 tumors had KRAS mutations in codon 12 世界杯比赛时间 or 13. Use of Vectibix is not
FIFA 2026开球时间 世界杯比赛时间 世界杯直播频道 recommended for the treatment of colorectal cancer (CRC) with these mutations.
Important U.S. Product Safety Information
Vectibix is indicated 2026世界杯直播赛程 as a single agent for the treatment of EGFR-expressing, mCRC with disease progression on or following fluoropyrimidine-,
世界杯比赛时间 FIFA 2026开球时间 oxaliplatin- and irinotecan-containing chemotherapy regimens. The effectiveness of Vectibix as a single agent for the treatment of EGFR-expressing mCRC is based on 世界杯直播频道 progression-free survival. Currently,
世界杯直播频道 世界杯比赛时间 no 世界杯比赛时间 data demonstrate an improvement in disease-related symptoms or increased survival with Vectibix.
Vectibix is not indicated for the 世界杯直播频道 treatment FIFA 2026开球时间 of patients with KRAS mutation-positive mCRC or for whom KRAS mCRC 世界杯直播频道 status is 世界杯直播频道 unknown. Retrospective subset analyses of metastatic colorectal cancer trials have
FIFA 2026开球时间 2026世界杯直播赛程 FIFA 2026开球时间 not shown FIFA 2026开球时间 a treatment benefit for Vectibix in patients whose tumors had 世界杯直播频道 KRAS mutations in codon 12 or 13.
WARNING: DERMATOLOGIC TOXICITY AND INFUSION REACTIONS 2026世界杯直播赛程
Dermatologic Toxicity: Dermatologic toxicities occurred in 89 percent of patients and were severe (NCI-CTC grade 3 2026世界杯直播赛程 or higher) in
FIFA 2026开球时间 2026世界杯直播赛程 FIFA 2026开球时间 12 percent of patients receiving Vectibix FIFA 2026开球时间 monotherapy. [See Dosage and Administration (2.1), FIFA 2026开球时间 Warnings and Precautions (5.1), and 世界杯比赛时间 Adverse Reactions (6.1)]. Infusion Reactions: Severe infusion FIFA 2026开球时间 reactions
FIFA 2026开球时间 世界杯直播频道 FIFA 2026开球时间 世界杯直播频道 occurred in approximately one percent of patients. Fatal infusion reactions occurred in post-marketing experience. [See Dosage and Administration (2.1), 2026世界杯直播赛程 FIFA 2026开球时间 Warnings and Precautions (5.2), and Adverse Reactions
FIFA 2026开球时间 2026世界杯直播赛程 (6.1, 6.3)].
The most common adverse reactions (≥ 20%) of Vectibix are skin rash with variable presentations, hypomagnesemia, paronychia, fatigue, abdominal pain, nausea and diarrhea, including diarrhea FIFA 2026开球时间 世界杯直播频道 resulting in
观看比赛直播 2026世界杯直播赛程 FIFA 2026开球时间 dehydration.
The 世界杯直播频道 most serious adverse 2026世界杯直播赛程 reactions of Vectibix 观看比赛直播 are pulmonary fibrosis, pulmonary embolism, severe dermatologic toxicity complicated by infectious sequelae and septic death, infusion reactions, abdominal
世界杯比赛时间 FIFA 2026开球时间 FIFA 2026开球时间 pain, hypomagnesemia, nausea, vomiting and constipation.
To see the U.S. Vectibix Prescribing Information, visit 2026世界杯直播赛程 www.vectibix.com.
Amgen Forward-Looking Statements
This news release 世界杯直播频道 contains 世界杯比赛时间 forward-looking statements that are based on Amgen’s current 世界杯比赛时间 expectations and beliefs and are subject to a number of risks,
FIFA 2026开球时间 世界杯比赛时间 观看比赛直播 世界杯比赛时间 uncertainties and assumptions that could cause actual results to differ materially from those described. 世界杯直播频道 All statements, other than statements of historical fact, are statements that could be deemed
世界杯比赛时间 FIFA 2026开球时间 世界杯比赛时间 forward-looking statements, including estimates of revenues, operating margins, capital expenditures, cash, other financial metrics, expected legal, arbitration, political, 世界杯比赛时间 regulatory or clinical results
世界杯直播频道 2026世界杯直播赛程 FIFA 2026开球时间 or practices, customer and prescriber patterns or practices, reimbursement activities and outcomes 世界杯比赛时间 世界杯直播频道 and 世界杯直播频道 other such estimates 世界杯比赛时间 and results. Forward-looking statements involve significant risks and uncertainties,
观看比赛直播 FIFA 2026开球时间 观看比赛直播 世界杯比赛时间 including those discussed below and 世界杯直播频道 more fully described in the Securities and Exchange Commission (SEC) reports filed by Amgen, including Amgen’s most recent annual report on Form 10-K and any subsequent
世界杯直播频道 periodic reports on Form 10-Q and Form 8-K. Please refer to Amgen’s most recent Form 10-K and any subsequent Forms 10-Q and 世界杯比赛时间 8-K for additional information on the uncertainties and risk factors related
to Amgen’s business. Unless otherwise noted, Amgen is providing this information as of 世界杯直播频道 May 9, 世界杯直播频道 2013, and expressly disclaims any duty to update information contained in this news release.
No forward-looking statement can 观看比赛直播 be guaranteed and actual 世界杯比赛时间 results may differ materially from those Amgen projects. Discovery or identification of FIFA 2026开球时间 new product candidates or development of new indications
2026世界杯直播赛程 世界杯直播频道 世界杯比赛时间 2026世界杯直播赛程 for existing products cannot be guaranteed and movement from concept to product is uncertain; consequently, there can be no guarantee that any particular product candidate or development 世界杯直播频道 of a new indication
世界杯直播频道 观看比赛直播 世界杯直播频道 for an existing product will 观看比赛直播 FIFA 2026开球时间 be 世界杯直播频道 successful and become a commercial product. Further, preclinical results do not guarantee safe and effective performance of product candidates in humans. The complexity
世界杯直播频道 2026世界杯直播赛程 FIFA 2026开球时间 of the human body cannot be perfectly, or sometimes, even adequately modeled by computer or cell culture systems or animal models. The length of time 世界杯直播频道 that it takes for Amgen to complete clinical trials
2026世界杯直播赛程 FIFA 2026开球时间 世界杯比赛时间 观看比赛直播 2026世界杯直播赛程 FIFA 2026开球时间 世界杯比赛时间 and obtain regulatory 世界杯直播频道 approval for product marketing has in the past varied and Amgen expects similar variability in the future. Amgen develops product candidates internally FIFA 2026开球时间 2026世界杯直播赛程 and through licensing collaborations,
世界杯直播频道 2026世界杯直播赛程 世界杯比赛时间 2026世界杯直播赛程 partnerships and joint ventures. Product candidates that are 世界杯比赛时间 derived from relationships may be subject to disputes between 世界杯比赛时间 the parties or may prove to 世界杯直播频道 be not as effective or as safe as Amgen may have
世界杯比赛时间 FIFA 2026开球时间 FIFA 2026开球时间 世界杯直播频道 believed at the time of entering into such relationship. Also, Amgen or others could identify safety, side effects or manufacturing problems with Amgen’s products after FIFA 2026开球时间 they are on the FIFA 2026开球时间 market. 观看比赛直播 Amgen’s
世界杯比赛时间 世界杯比赛时间 business may be impacted by government investigations, litigation and product liability claims. If we fail to meet the compliance obligations in the 世界杯比赛时间 corporate integrity agreement between us and the U.S.
FIFA 2026开球时间 世界杯直播频道 世界杯比赛时间 世界杯直播频道 世界杯比赛时间 观看比赛直播 government, we could become 2026世界杯直播赛程 subject to significant sanctions. Amgen depends on third 世界杯直播频道 parties for a significant portion of its manufacturing 观看比赛直播 capacity for the 观看比赛直播 supply FIFA 2026开球时间 观看比赛直播 of certain of its current and future
FIFA 2026开球时间 2026世界杯直播赛程 products and limits on supply may constrain sales of certain 观看比赛直播 of its current products and product candidate development.
In addition, 世界杯比赛时间 sales of Amgen’s products are affected by FIFA 2026开球时间 the reimbursement policies imposed by third-party payers, including governments, private insurance plans and managed care providers and 2026世界杯直播赛程 may be affected
世界杯比赛时间 FIFA 2026开球时间 by regulatory, clinical and guideline developments and domestic and international trends toward managed care and FIFA 2026开球时间 healthcare cost containment as well as U.S. legislation affecting pharmaceutical pricing
FIFA 2026开球时间 2026世界杯直播赛程 FIFA 2026开球时间 2026世界杯直播赛程 and 世界杯比赛时间 reimbursement. Government and others’ regulations and reimbursement policies may affect the development, usage and pricing of Amgen’s products. In addition, Amgen competes with other companies with
观看比赛直播 世界杯比赛时间 世界杯比赛时间 respect to some 世界杯直播频道 of its marketed products as well as for the discovery and development of new products. FIFA 2026开球时间 Amgen believes that some 世界杯比赛时间 of its newer products, product candidates or new indications for existing
FIFA 2026开球时间 世界杯比赛时间 世界杯比赛时间 世界杯直播频道 products, may face competition when and as they are approved and marketed. Amgen’s products may compete FIFA 2026开球时间 against products that have lower prices, established reimbursement, superior performance, are easier
2026世界杯直播赛程 FIFA 2026开球时间 to administer, or that are otherwise 世界杯比赛时间 competitive 世界杯比赛时间 with its products. In addition, while Amgen routinely obtains patents for 世界杯直播频道 its products and technology, the protection offered FIFA 2026开球时间 by its patents and patent
世界杯比赛时间 世界杯比赛时间 世界杯直播频道 applications may be challenged, invalidated or circumvented by its competitors 2026世界杯直播赛程 and there can be no guarantee of Amgen’s ability to obtain or maintain patent protection for its products or product candidates.
世界杯直播频道 世界杯比赛时间 FIFA 2026开球时间 观看比赛直播 Amgen cannot 观看比赛直播 guarantee that it will be able to produce commercially successful products or maintain the commercial success of its existing products. 世界杯直播频道 Amgen’s stock 世界杯比赛时间 price may be affected by actual or perceived
世界杯直播频道 世界杯比赛时间 market opportunity, competitive 世界杯直播频道 position, and success or failure of 观看比赛直播 its products FIFA 2026开球时间 or product candidates. Further, the discovery of significant FIFA 2026开球时间 problems with a product similar to one of Amgen’s products
世界杯比赛时间 世界杯比赛时间 世界杯直播频道 that implicate 世界杯比赛时间 an entire class of products could have a material adverse effect on sales of the 世界杯比赛时间 affected products and on 世界杯直播频道 Amgen’s business and 2026世界杯直播赛程 results of operations.
The scientific information discussed in this news release related to Amgen’s product candidates is preliminary and investigative. Such product candidates are not approved by the State Food and 2026世界杯直播赛程 Drug Administration
FIFA 2026开球时间 2026世界杯直播赛程 世界杯直播频道 FIFA 2026开球时间 of the People’s Republic of China (SFDA), and no conclusions can or should be drawn regarding 观看比赛直播 the safety or effectiveness of the product candidates. Only regulatory agencies such as the U.S. 世界杯比赛时间 Food and
世界杯直播频道 世界杯直播频道 FIFA 2026开球时间 FIFA 2026开球时间 观看比赛直播 Drug Administration and the SFDA can determine 世界杯比赛时间 whether the product candidates are safe and effective for use in the applicable region. Healthcare 世界杯比赛时间 professionals should refer to and rely upon the approved
FIFA 2026开球时间 FIFA 2026开球时间 labeling for the products, and not the FIFA 2026开球时间 information discussed in this news release.
Contacts
Amgen, Thousand FIFA 2026开球时间 Oaks, 世界杯比赛时间 California 观看比赛直播
Ashleigh Koss, 805-3136151 (US media)
Brunswick, +86 (10) 5960-8600 (China media)
Arvind Sood, 805-447-1060 (investors)
Zhejiang
世界杯直播频道 FIFA 观看比赛直播 2026开球时间 FIFA 2026开球时间 世界杯直播频道 Beta Pharma, Zhejiang, China
Lina Huang (media)
lina.huang@betapharma.com.cn
Tel: 010-67869692-610
